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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN446 描述 Anti-Capicua Antibody Alternate Names - Protein capicua homolog
背景信息 Protein capicua homolog (CIC) , also known as Capicua Transcriptional Repressor, Capicua Homolog, and encoded by the gene CIC, is a transcriptional repressor which plays a role in development of the central nervous system (CNS). CIC is a new subfamily of the HMG-box superfamily and the gene's expression is predominantly restricted to immature granule cells in the cerebellum, hippocampus and olfactory bulb in the CNS, and thus the gene is implicated in CNS development, in particular in granule cell development. CIC appears to be central to cerebellar development and ErbB signaling as well. Recent research has demonstrated that CIC is highly expressed in certain cancers including medulloblastomas, but also the loss of expression may serve as a biomarker for other cancer types such as oligodendrogliomas. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Capicua Antibody is validated for use in Western Blotting for the detection of Capicua. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50-1,000 dilution from a representative lot detected Capicua in human cerebral cortex tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Capicua near the N-terminal. 表位 Near N-terminal 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Human. Predicted to react with Mouse, Hamster, Rat, Chimpanzee, Ox based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_055940
基因符号 - CIC
纯化方法 Affinity purified UniProt编号 - Q96RK0
产品使用声明 质量保证 Evaluated by Western Blotting in human cerebellum tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Capicua in 10 µg of human cerebellum tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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