merck millipore,默克密理愽
  • merck millipore,默克密理博,219505,CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem

  • merck millipore,默克密理博,219505,CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem

    产品名称：CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem
    产品型号：219505
    The CBFβ Inhibitor, also referenced under CAS 493028-20-9, controls the biological activity of CBFβ.

    merck millipore,默克密理博,219505,CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219505,CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₂H₁₄N₂OS493028-20-9
    描述
    概述 A cell-permeable thiazolyl compound that binds to CBFβ (core binding factor β) and allosterically disrupts CBFα/Runx1 binding to CBFβ both in cell-free binding studies (IC50 of ~3.5 µM by FRET and ELISA) and in HEK293 cells (IC50 of ~ 100 µM by FACS/FRET). Cellular studies indicate a good correlation between the inhibitor's antiproliferative activity and the Runx1 expression level in the target cells.
    产品目录编号 219505
    品牌系列 Calbiochem®
    同义词 5-Ethyl-4-(4ʹ-methoxyphenyl)-thiazolyl-2-amine, CBFα-CBFβ Inhibitor I, CBFβ-Runx1 Inhibitor I
    参考
    参考 Gorczynski, M.J., et al. 2007. Chem. Biol. 14, 1186.
    产品信息
    CAS号 493028-20-9
    形式 Tan solid
    Hill配方 C₁₂H₁₄N₂OS
    化学配方 C₁₂H₁₄N₂OS
    Molar Mass 234.3
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    安全信息
    S相 S: 24/25

    Avoid contact with skin and eyes.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

    merck millipore,默克密理博,219505,CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem

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