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merck millipore,默克密理博,ABN444,Anti-Amyloid-like protein 1 Antibody
产品名称：Anti-Amyloid-like protein 1 Antibody
产品型号：ABN444
This Anti-Amyloid-like protein 1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Amyloid-like protein 1.
merck millipore,默克密理博,ABN444,Anti-Amyloid-like protein 1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN444 描述 Anti-Amyloid-like protein 1 Antibody Alternate Names - Amyloid-like protein-1
- APLP-1
- APLP
- APLP1
背景信息 Amyloid-like protein 1 or APLP-1 is neuronal, membrane bound specific protein that likely has a role in post-synaptic function but most research has focused on its proteolytic fragments such as ALID1 which acts as a transcriptional activator through binding the co-activator APBB1. APLP-1 fragments also interact with various G-protein coupled receptor pathways and appear to have a role in synaptic maturation during cortical development. APLP-1 also appears to regulate neurite outgrowth through binding to components of the ECM such as heparin and collagen I. Finally a special fragment called C30 is a potent enhancer of neuronal apoptosis and is a caspase specific cleavage fragment that works internally inducing apoptosis. Thus APLP-1 has roles in apoptosis, cell adhesion, endocytosis, cell signaling and neurite extension as well as some post-synaptic function as it is found clustered at post-synaptic densities in normal cells. 产品信息 格式 Affinity Purified 演示 Purified Rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Amyloid-like protein 1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Amyloid-like protein 1. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Amyloid-like protein 1 in human cerebral cortex and thalamic tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the extracellular domain of Human Amyloid-like protein 1. 表位 Extracellular domain 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Human. Predicted to react with Rat, Mouse based on 100% sequence homology. Immunogen is 94% identical to Bovine 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005157
基因符号 - APLP1
纯化方法 Antigen Affinity purified UniProt编号 - P51693
产品使用声明 质量保证 Evaluated by Western Blotting in Human Cortex tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Amyloid-like protein 1 in 10 µg of Human Cortex tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,14-440M,PKA Protein, Recombinant, 250 µg
下一件merck millipore产品：merck millipore,默克密理博,MAB348B,Anti-Alzheimer Precursor Protein A4 Antibody, clone 22C11, Biotin Conj.,MAB348B
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