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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN413 描述 Anti-WWOX Antibody Alternate Names - Fragile site FRA16D oxidoreductase
- WW domain-containing oxidoreductase
背景信息 WW domain-containing oxidoreductase (WWOX) is also called Fragile site FRA16D oxidoreductase (FOR). WWOX is a putative oxidoreductase that functions as a tumor suppressor and is involved in apoptosis. WWOX is also required for normal bone development, and inhibits Wnt signaling. WWOX is widely expressed, but is most strongly expressed in testis, prostate, and ovary as well as in cancer cell lines. Certain isoforms (Isoform 5 and isoform 6) are thought to only be expressed in tumor cell lines. WWOX is linked to several cancer types like Esophageal cancer (ESCR). 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-WWOX Antibody is a highly specific rabbit polyclonal antibody, that targets WWOX & has been tested in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected WWOX in human prostate cancer sections and human ovary sections tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the N-Terminus of human WWOX. 表位 N-Terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHuman Species Reactivity Note Human, Mouse. Predicted to react with Rat and Bovine based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_057457
基因符号 - WOX1
- WWOX
- FOR
纯化方法 Affinity purified UniProt编号 - Q9NZC7
产品使用声明 质量保证 Evaluated by Western Blotting in HepG2 cell lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected WWOX in 10 µg of HepG2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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