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  • merck millipore,默克密理博,ABE558,Anti-Ku70 Protein Antibody

  • merck millipore,默克密理博,ABE558,Anti-Ku70 Protein Antibody

    产品名称：Anti-Ku70 Protein Antibody
    产品型号：ABE558
    Detect Ku70 Protein using this rabbit polyclonal antibody, Anti-Ku70 Protein Antibody validated for use in western blotting, IP & IHC (Paraffin).

    merck millipore,默克密理博,ABE558,Anti-Ku70 Protein Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABE558,Anti-Ku70 Protein Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 ABE558
    Replaces AB1358
    描述 Anti-Ku70 Protein Antibody
    Alternate Names
    • X-ray repair complementing defective repair in Chinese hamster cells 6
    • X-ray repair cross-complementing protein 6
    • 5'-deoxyribose-5-phosphate lyase Ku70
    • 5'-dRP lyase Ku70
    • 70 kDa subunit of Ku antigen
    • ATP-dependent DNA helicase 2 subunit 1
    • ATP-dependent DNA helicase II 70 kDa subunit
    • CTC box-binding factor 75 kDa subunit
    • CTC75
    • CTCBF
    • DNA repair protein XRCC6
    • Lupus Ku autoantigen protein p70
    • Ku70
    • Thyroid-lupus autoantigen
    • TLAA
    背景信息 Lupus Ku autoantigen protein p70 (Ku70) is also known as X-ray repair cross-complementing protein 6 (XRCC6), 5'-dRP lyase Ku70, CTC box-binding factor 75 kDa subunit (CTC75, CTCBF) or Thyroid-lupus autoantigen (TLAA). Ku70 is a single stranded DNA-dependent ATP-dependent helicase that plays a role in chromosome translocation and DNA non-homologous end joining (NHEJ) required for double-strand break repair and recombination. The XRCC5/6 (Ku80/Ku70) dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK, and that dimer, together with APEX1, acts as a negative regulator of transcription. Individuals with systemic lupus erythematosus (SLE) and related disorders produce extremely large amounts of autoantibodies to XRCC5 (Ku80) and XRCC6 (Ku70).
    产品信息
    格式 Purified
    控制
    • HeLa cell lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect Ku70 Protein using this rabbit polyclonal antibody, Anti-Ku70 Protein Antibody validated for use in western blotting, IP & IHC (Paraffin).
    主要应用
    • Western Blotting
    应用说明 Immunoprecipitation Analysis: A representative lot immunoprecipitated Ku70 Protein in 0.5 mg of HeLa cell lysate.
    Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Ku70 Protein in human prostate carcinoma cells and human testis tissue.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human Ku70 Protein near N-Terminus.
    表位 Near N-Terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 This antibody recognizes Ku70 Protein near N-Terminus.
    品种反应性 Human
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_001460
    基因符号
    • G22P1
    • XRCC6
    纯化方法 Protein A purified
    UniProt编号
    • P12956
    产品使用声明
    质量保证 Evaluated by Western Blotting in HeLa cell lysate.

    Western Blotting Analysis: 0.5 µg/mL of this antibody detected Ku70 Protein in 10 µg of HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABE558,Anti-Ku70 Protein Antibody

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