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merck millipore,默克密理博,ABE533,Anti-acetyl Histone H4 Antibody (Lys16)
产品名称:Anti-acetyl Histone H4 Antibody (Lys16)
产品型号:ABE533
Anti-acetyl Histone H4 Antibody (Lys16) is a highly specific rabbit polyclonal antibody, that targets Histone H4 & has been tested in western blotting & Dot Blot.
merck millipore,默克密理博,ABE533,Anti-acetyl Histone H4 Antibody (Lys16)
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H, Yeast ChIP, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 ABE533 描述 Anti-acetyl Histone H4 Antibody (Lys16) Alternate Names - Histone H4
背景信息 Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The histones have an amino terminal tail, a globular domain, and a carboxy-terminal tail. The four core histones, H2A, H2B, H3 and H4 assemble into the octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped in a sequence-independent manner around the octamer, forming the basic subunit of chromatin, the nucleosome. Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). 产品信息 格式 Serum 演示 Rabbit polyclonal serum containing 0.0002% thimerosal. 应用 应用 Anti-acetyl Histone H4 Antibody (Lys16) is a highly specific rabbit polyclonal antibody, that targets Histone H4 & has been tested in western blotting & Dot Blot. 主要应用 - Chromatin Immunoprecipitation (ChIP)
- Western Blotting
应用说明 Dot Blot Analysis: A 1:1,000 dilution from a representative lot detected acetyl Histone H4 (Lys16) in a panel of Histone H2A, H2B, and H4 recombinant proteins.
Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory detected acetyl Histone H4 (Lys8) in certain yeast strains transfected with wildtype or mutant Histone H4 (Suka, N., et al. (2001). Mol Cell. 8(2):473-479.).生物信息 免疫原品种 Ovalbumin-conjugated linear peptide corresponding to yeast Histone H4 acetylated at Lys16. 宿主 Rabbit 品种反应性 HumanYeast Species Reactivity Note Demonstrated to react with Yeast and Human. Predicted to react with Mouse and Rat based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_009563
基因符号 - HHF2
- HHF1
修改 - Acetylation
纯化方法 Unpurified UniProt编号 - P02309
产品使用声明 质量保证 Evaluated by Western Blotting in untreated and sodium butyrate treated HeLa acid extract.
Western Blotting Analysis: 1:1,000 dilution from a representative lot detected acetyl Histone H4 (Lys16) in 10 µg of sodium butryate treated HeLa acid extract and demonstrated a loss of signal in untreated HeLa acid extract.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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