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merck millipore,默克密理博,ABE501,Anti-phospho IRF3 (ser386) Antibody
产品名称：Anti-phospho IRF3 (ser386) Antibody
产品型号：ABE501
Detect IRF-3 using this rabbit polyclonal antibody, Anti-phospho IRF3 (ser386) Antibody validated for use in western blotting.
merck millipore,默克密理博,ABE501,Anti-phospho IRF3 (ser386) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE501 描述 Anti-phospho IRF3 (ser386) Antibody Alternate Names - IRF-3
- Interferon regulatory factor 3
背景信息 Interferon regulatory factors (IRFs) comprise a family of transcription factors that function with the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response. In unstimulated cells, IRF-3 is present in the cytoplasm. Viral infection results in phosphorylation of IRF-3 and leads to its translocation to the nucleus where it activates promoters containing IRF-3-binding sites. Phosphorylation of IRF-3 occurs at a cluster of C-terminal serine and threonine residues (between 385 and 405) leading to its association with the p300/CBP coactivator protein that promotes DNA binding and transcriptional activity. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect IRF-3 using this rabbit polyclonal antibody, Anti-phospho IRF3 (ser386) Antibody validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human IRF3 (ser386) near the C-terminus. 表位 Near C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Human. Predicted to react with Rhesus Macaque based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001562
基因符号 - IRF3
纯化方法 Affinity purified UniProt编号 - Q14653
产品使用声明 质量保证 Evaluated by Western Blotting in MCF7 cell lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected detected IRF3 (ser386) in 10 µg of Calyculin A treated MCF7 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,420320,KT5720 - CAS 108068-98-0 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,14-531,EGFR Protein, active, 10 µg
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