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merck millipore,默克密理博,23-027M,b-catenin Protein, activated, 250 µg
产品名称:b-catenin Protein, activated, 250 µg
产品型号:23-027M
Activated, full length, recombinant human β-catenin. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using GSK-3a. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.
merck millipore,默克密理博,23-027M,b-catenin Protein, activated, 250 µg
- 产品介绍
重要规格表
主要应用 品种 级联部件 EA Human Substrate 描述 产品目录编号 23-027M 品牌系列 Upstate
商名 - Upstate
描述 b-catenin Protein, activated, 250 µg 长描述 N-terminal c-Myc, 6His-tagged, recombinant human β-catenin full length, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography. Phosphorylated in vitro using GSK-3a (Item # 14-492). Alternate Names - Catenin beta-1
背景信息 β-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion complex, regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that governs cell fate in early embryogenesis. The regulation of β-catenin turnover in the cells is governed by its phosphorylation status which allows the targeting of ubiquitin-dependent proteolysis. Altered levels of protein expression as well as genetic mutations of β-catenin have been implicated in a number of human cancers. 应用 应用 Activated, full length, recombinant human β-catenin. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using GSK-3a. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays. 主要应用 - Enzyme Assay
生物信息 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. 级联部件 Substrate Entrez基因编号 - NM_001904 (GenBank Number)
纯化方法 Purified using immobilized metal affinity chromatography. 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 250 µg
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