merck millipore,默克密理博,ABE500,Anti-WBP-7 Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABE500
描述	Anti-WBP-7 Antibody
Alternate Names	WBP-7 Histone-lysine N-methyltransferase MLL4 Lysine N-methyltransferase 2B KMT2B Myeloid/lymphoid or mixed-lineage leukemia protein 4 Trithorax homolog 2 WW domain-binding protein 7
背景信息	WW domain-binding protein 7 (WBP-7) is also called Histone-lysine N-methyltransferase MLL4, Lysine N-methyltransferase 2B (KMT2B), Myeloid/lymphoid or mixed-lineage leukemia protein 4 and Trithorax homolog 2. WBP-7 is a histone methyltransferase that methylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation. WBP-7 is important in beta-globin locus transcription regulation and for controlling bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing, oocyte survival and normal zygotic genome activation during oocyte growth and development. WBP-7 is widely expressed with the highest levels in testis. WBP-7 is also detected in brain, bone marrow, heart, muscle, kidney, placenta, spleen, thymus, prostate, ovary, intestine, colon, peripheral blood lymphocytes and pancreas and is found to often be amplified in pancreatic carcinomas.

产品信息
格式	Affinity Purified
控制	MCF7 cell lysate
演示	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect WW domain-binding protein 7 using this rabbit polyclonal antibody, Anti-WBP-7 Antibody validated for use in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to human WBP-7 near the C-Terminus.
表位	Near C-Terminus
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	This antibody recognizes WBP-7 near the C-Terminus.
品种反应性	RatHumanMouse
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_055542
基因符号	TRX2 WBP7 HRX2 KIAA0304 KMT2B MLL2 MLL4
纯化方法	Affinity purified
UniProt编号	Q9UMN6

产品使用声明
质量保证	Evaluated by Western Blotting in MCF7 cell lysate. Western Blotting Analysis: 2.0 µg/mL of this antibody detected MCF7 in 10 µg of MCF7 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABE500,Anti-WBP-7 Antibody

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