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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ChIP, WB Rb Purified Polyclonal Antibody 描述 产品目录编号 ABE479 描述 Anti-hMOF Antibody Alternate Names - hMOF
- Histone acetyltransferase KAT8
- Lysine acetyltransferase 8
- MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1
- MYST-1
背景信息 hMOF, also known as Histone acetyltransferase KAT8, or Lysine acetyltransferase, MOZ, YBF2/SAS3, SAS2, TIP60 protein 1, and MYST-1, and encoded by the gene KAT8/MOF/MYST1, is a histone acetyltransferase which is involved in transcriptional activation and also is a component of the MSL complex involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. hMOF also a component of many other MSL related complexes including the methyltransferase complexes and interacts with numerous other related proteins including BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MOF/KAT8, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. hMOF is localized to the nucleus and nuclear chromosomes. 产品信息 格式 Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-hMOF antibody detects level of hMOF & has been published & validated for use in hMOF. 主要应用 - Chromatin Immunoprecipitation (ChIP)
- Western Blotting
应用说明 Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated hMOF from HeLa cell lysate (Wu, L., et al. (2011). Mol Cell. 43(1):132-144.).
Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated hMOF from HeLa cell lysate (Smith, E. R., et al. (2005). Mol Cell Biol. 25(21):9175-9188.).
生物信息 免疫原品种 Linear peptide corresponding to hMOF. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_115564
基因符号 - MYST1
- KAT8
- MOF
纯化方法 Protein G purified UniProt编号 - Q9H7Z6
产品使用声明 质量保证 Evaluated by Western Blotting in HUVEC cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected hMOF in 10 µg of HUVEC cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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