merck millipore,默克密理愽
  • merck millipore,默克密理博,681664,Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem

  • merck millipore,默克密理博,681664,Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem

    产品名称：Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem
    产品型号：681664
    The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.

    merck millipore,默克密理博,681664,Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,681664,Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₁₈N₄O₃853220-52-7
    描述
    概述 A cell-permeable, potent, and selective activator of Wnt signaling that does not inhibit the activity of GSK-3β (IC50 >60 µM). Shown to mimic the effect of Wnt and induce β-catenin and TCF (T-cell fate)-dependent transcriptional activity (EC50 = 700 nM in HEK-293T cells). Reported to cause substantial head defects during Xenopus embryonic development. The solid form of this compound (Cat. No. 681665) is also available.
    产品目录编号 681664
    品牌系列 Calbiochem®
    同义词 Wnt Pathway Activator I in DMSO, 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine
    参考
    参考 Liu, J., et al. 2005. Angew. Chem. Int. Ed. 44, 1987.
    产品信息
    CAS号 853220-52-7
    形式 Liquid
    配方 A 25 mM (2 mg/228 µL) solution of Wnt Agonist I (Cat. No. 681665) in DMSO.
    Hill配方 C₁₉H₁₈N₄O₃
    Molar Mass 350.4
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    安全信息
    R相 R: 36/38

    Irritating to eyes and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Irritant
    储存 ≤ -70°C
    避光 Protect from light
    吸湿 Hygroscopic
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,681664,Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem

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