merck millipore,默克密理博,ABE477,Anti-BRD2 Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, H	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABE477
描述	Anti-BRD2 Antibody
Alternate Names	Bromodomain-containing protein 2 O27.1.1 Really interesting new gene 3 protein
背景信息	Bromodomain-containing protein 2 (BRD2) is a member of the BET subfamily of bromodomain proteins. These proteins contain two tandem N-terminal bromodomains and a single C-terminal extra-terminal domain. Studies have shown BRD2 to be associated with several regulators of transcription (eg. TFIID and Swi/Snf complexes) in addition to its involvement in guiding cell cycle gene expression through its binding to multiple E2F. BRD2 is hypothesized to function in mammalian development by regulating chromatin structure and transcription. Consistent with this hypothesis, studies have shown BRD2 to bind histone H4 via acetylated Lys12. BRD2 mutants have been associated with increased susceptibility to juvenile myoclonic epilepsy.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Anti-BRD2 Antibody is a highly specific rabbit polyclonal antibody, that targets BRD2 & has been tested in western blotting & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:500 dilution of this antibody from a representative lot detected BRD2 in human testis tissues. Immunohistochemistry Analysis: A 1:2,000 and a 1:500 dilution from a representative lot detected BRD2 in rat testis tissues.

生物信息
免疫原品种	GST-tagged recombinant protein corresponding to a region near the C-terminus of human BRD2.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	This antibody is expected to cross react with isoforms 1 and 2 of BRD2, based upon sequence homology.
品种反应性	RatHuman
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_001106653.1
基因符号	RING3 BRD2
纯化方法	Affinity purified
UniProt编号	P25440

产品使用声明
质量保证	Evaluated by Western Blotting in Jurkat cell lysate. Western Blotting Analysis: 0.25 µg/mL of this antibody detected BRD2 in 10 µg of Jurkat cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABE477,Anti-BRD2 Antibody

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