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品种反应性 主要应用 宿主 格式 抗体类型 M, H, R ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE364 描述 Anti-Tet2 Antibody Alternate Names - Methylcytosine dioxygenase TET2
背景信息 Methylcytosine dioxygenase TET2 catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). The function of 5-hydroxymethylcytosine is currently unclear but it may influence chromatin structure, or act as an intermediate component in cytosine demethylation. TET2 is frequently mutated in myeloproliferative disorders (MPD) or myeloproliferative neoplasms (MPN), and systemic mastocytosis. TET2 disorders also cause polycythemia vera (PV) and myelodysplastic syndrome (MDS). 产品信息 格式 Affinity Purified 控制 - Mouse Embryonic Stem cells
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Tet2 detects levels of Tet2 proteins & has been published & validated for use in WB, IHC & ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:4,000 dilution from a representative lot detected Tet2 in rat medulla tissue.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected Tet2 in human H9 Embryonic Stem cells.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Tet2. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHumanRat Species Reactivity Note Demonstrated to react with Human, Rat, and Mouse. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_060098
基因符号 - TET2
纯化方法 Affinity purified UniProt编号 - Q6N021
产品使用声明 质量保证 Evaluated by Western Blotting in mouse Embryonic Stem cells.
Western Blotting Analysis: 1 µg/mL of this antibody detected Tet2 in 10 µg of mouse Embryonic Stem cells (Note: Isoforms 2 and 3 may observed at low concentrations or longer exposure times, while isoform 1 may be detected at higher concentrations or longer exposure times in certain cell lysates.).使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,46-623MAG,MILLIPLEX MAP Phospho STAT3 (Tyr705) Magnetic Bead MAPmate - Cell Signaling Single Plex or Multiplex Assay
下一件merck millipore产品：merck millipore,默克密理博,MAB3440,Anti-Factor VIII Antibody, 83 kDa light chain, clone 24-2-C7
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