merck millipore,默克密理博,ABE321,Anti-dimethyl Histone H4 Antibody (Arg19), Symmetric

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABE321
描述	Anti-dimethyl Histone H4 Antibody (Arg19), Symmetric
Alternate Names	Histone H4
背景信息	Histone H4 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H4 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect Histone H4 using this rabbit polyclonal antibody, Anti-dimethyl Histone H4 Antibody (Arg19), Symmetric validated for use in western blotting & Dot Blot.
主要应用	Western Blotting
应用说明	Dot Blot (Specificity) Analysis: 3 µg/mL of this antibody detected Histone H4 symmetrically dimethylated at Arg19 and not non-modified Histone H3 or other peptides corresponding to modified histones. Dot Blot was performed using an Absurance™ Histone H3 Antibody Specificity Array (Cat. No. 16-667) and an Absurance™ Histone H2A, H2B, H4 Antibody Specificity Array (Cat. No. 16-665).

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to the N-terminus of human Histone H4 symmetrically dimethylated at Arg19.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	This antibody cross reacts with Histone H4 symmetrically dimethylated at Arg19.
品种反应性	Human
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_001029249
基因符号	HIST4H4 HIST1H4A H4/A H4FA HIST1H4B H4/I H4FI HIST1H4C H4/G H4FG HIST1H4D H4/B H4FB HIST1H4E H4/J H4FJ HIST1H4F H4/C H4FC HIST1H4H H4/H H4FH HIST1H4I H4/M H4FM HIST1H4J H4/E H4FE HIST1H4K H4/D H4FD HIST1H4L H4/K H4FK HIST2H4A H4/N H4F2 H4FN HIST2H4 HIST2H4B H4/O H4FO
修改	Methylation
纯化方法	Affinity purified
UniProt编号	P62805

产品使用声明
质量保证	Evaluated by Western Blotting in using Histone H4 symmetrically dimethylated at Arg19. Western Blotting Analysis: 1 µg/mL of this antibody detected Histone H4 symmetrically dimethylated at Arg19, and not unmethylated Histone H4, or other peptides corresponding to modified histones.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABE321,Anti-dimethyl Histone H4 Antibody (Arg19), Symmetric

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