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merck millipore,默克密理博,ABE302,Anti-ATDC Antibody
产品名称：Anti-ATDC Antibody
产品型号：ABE302
Anti-ATDC Antibody is a Rabbit Polyclonal Antibody for detection of ATDC also known as Ataxia telangiectasia group D-associated protein & has been validated in WB & IP.
merck millipore,默克密理博,ABE302,Anti-ATDC Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE302 描述 Anti-ATDC Antibody Alternate Names - tripartite motif containing protein 29
- Ataxia telangiectasia group D-associated protein
背景信息 Ataxia telangiectasia group D-complementing (ATDC) protein, also known as tripartite motif containing protein 29 (TRIM29), belongs to the TRIM protein family. Studies have shown that ATDC may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. The ATDC gene is located at 11q23 where loss of heterozygosity has been observed in many kinds of cancers; underexpression of ATDC has been reported in breast and prostate cancer. ATDC may also complement the radiosensitivity defect of ataxia telangiectasia phenotype. 产品信息 格式 Affinity Purified 控制 - RAW 264.7 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-ATDC Antibody is a Rabbit Polyclonal Antibody for detection of ATDC also known as Ataxia telangiectasia group D-associated protein & has been validated in WB & IP. 主要应用 - Western Blotting
应用说明 Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in IP. (Yuan, Z., et al. (2010). J Biol Chem. 285(50):39329-39338.) 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to a region within amino acides 565 to 595 of human ATDC . 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_036233
Entrez基因汇总 The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]. 基因符号 - ATDC
- TRIM29
纯化方法 Affinity purified UniProt编号 - Q14134
UniProt汇总 FUNCTION: It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.
SUBUNIT STRUCTURE: Interacts with VIM and HINT1.
SUBCELLULAR LOCATION: Cytoplasm. Note: Colocalizes with intermediate filaments.
TISSUE SPECIFICITY: Expressed in placenta, prostate and thymus.
PTM: Constitutively phosphorylated by PKC on serine/threonine in A431 cells.
SEQUENCE SIMILARITIES: Contains 1 B box-type zinc finger.产品使用声明 质量保证 Evaluated by Western Blot in RAW 264.7 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected ATDC on 10 µg of RAW 264.7 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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