merck millipore,默克密理博,ABC61,Anti-NIPP-1 Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M, H	ICC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABC61
描述	Anti-NIPP-1 Antibody
Alternate Names	ARD-1 Nuclear inhibitor of protein phosphatase 1 NIPP-1 Protein phosphatase 1 regulatory inhibitor subunit 8
背景信息	Also known as ARD1 (Activator of RNA decay), NIPP-1 (nuclear inhibitor of protein phosphatase 1) is a ubiquitously expressed multifunctional nuclear scaffold protein of 39 kDa, which plays an important role in integrating transcription, RNA processing, and cell cycle progression. NIPP-1 serves as a signaling hub in the nucleus. Additionally, NIPP-1 contains at least two binding sites for PP1 and is complexed to about one-third of the nuclear pool of PP1. Normally, the NIPP-1 - PP1 complex is inactive, but can be activated following phosphorylation of NIPP-1 with PKA, CFK2, or Src family kinases. NIPP-1 also interacts directly with nucleic acids and components of polycomb repressive complexe 2 (PRC2) and functions as a PRC2-dependent transcriptional repressor.

产品信息
格式	Affinity Purified
控制	Raji nuclear extract
演示	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	This NIPP-1 antibody is validated for use in WB & ICC for the detection of the NIPP-1 protein.
主要应用	Immunocytochemistry Western Blotting
应用说明	Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected NIPP-1 in Raji cells.

生物信息
免疫原品种	GST-tagged recombinant protein corresponding to human NIPP-1.
宿主	Rabbit
特异性	This antibody should recognize the alpha and beta isoforms of NIPP-1.
品种反应性	MouseHuman
Species Reactivity Note	Demonstrated to react with Human and Mouse.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_002704
基因符号	NIPP1 PPP1R8 ARD1
纯化方法	Affinity purified
UniProt编号	Q12972

产品使用声明
质量保证	Evaluated by Western Blot Analysis in Raji nuclear extract. Western Blot Analysis: A 1:1,000 dilution from a representative lot detected NIPP-1 in 10 µg of Raji nuclear extract.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,ABC61,Anti-NIPP-1 Antibody

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