merck millipore,默克密理愽
  • merck millipore,默克密理博,ABC424,Anti-Sec23A Antibody

  • merck millipore,默克密理博,ABC424,Anti-Sec23A Antibody

    产品名称：Anti-Sec23A Antibody
    产品型号：ABC424
    Detect Sec23a using this rabbit polyclonal antibody, Anti-Sec23A Antibody validated for use in western blotting.

    merck millipore,默克密理博,ABC424,Anti-Sec23A Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABC424,Anti-Sec23A Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, MWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABC424
    描述 Anti-Sec23A Antibody
    Alternate Names
    • SEC23-related protein A
    • Protein transport protein Sec23A
    背景信息 The protein named Sec23a, also known as Sec23r, and encoded by the gene Sec23a/Sec23/Sec23r is a component of the COPII coat complex; this complex is the complex that governs ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. The transport of proteins in eukaryotic cells from the endoplasmic reticulum (ER) to the Golgi complex proceeds by deformation of specialized portions of the donor membrane to form carrier vesicles. A group of cytosolic proteins collectively known as COPII carry out a programmed set of sequential interactions, leading to cargo sorting and vesicle budding. The Sec23A protein is critical to proper protein transport in and out of cells, and it is localized to the smooth endoplasmic reticulum membrane where it is a peripheral membrane protein and interacts with the Golgi apparatus membranes as well. Sec23A is expressed at high levels in brain and fibroblasts as well as liver and other metabolically active tissues. Sec23A interacts with SEC23IP, HTR4, SEC16A and SLC6A proteins. Sec23A also appears to play a role directly in development as recent research linked Sec23A promoters to important developmental transcription factors such as TFII-1 and showed that important craniofacial and dental developmental genes could contribute to the WBS-specific facial dysmorphism in Williams-Beuren syndrome.
    产品信息
    格式 Affinity Purified
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect Sec23a using this rabbit polyclonal antibody, Anti-Sec23A Antibody validated for use in western blotting.
    主要应用
    • Western Blotting
    应用说明 Western Blotting Analysis: 1 µg/mL from a representative lot detected Sec23A in 10 µg of mouse heart, thymus, pancreas, testis, and adrenal gland tissues.

    Western Blotting Analysis: A representative lot from an independent laboratory detected Sec23A in various mouse tissues expressing wildtype Sec23A (Tao, J., et al. (2012). Proc Natl Acad Sci USA. 109(29):E2001-2009.).
    生物信息
    免疫原品种 Linear peptide corresponding to mouse Sec23A.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    品种反应性 RatMouse
    Species Reactivity Note Demonstrated to react with Mouse and Rat. Predicted to react with Human based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_033173
    基因符号
    • Sec23r
    • Sec23a
    • Sec23
    纯化方法 Affinity purified
    UniProt编号
    • Q01405
    产品使用声明
    质量保证 Evaluated by mouse brain tissue lysate.

    Western Blotting Analysis: 1 µg/mL of this antibody detected Sec23A in 10 µg of mouse brain tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABC424,Anti-Sec23A Antibody

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下一件merck millipore产品：merck millipore,默克密理博,559405,SB 225002 - CAS 182498-32-4 - Calbiochem


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