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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC423 描述 Anti-RAB8A Antibody Alternate Names - RAB8A
- Ras-related protein Rab-8A
- Oncogene c-mel
背景信息 Ras-related protein Rab-8A (RAB8A) is one of two Rab8 isoforms, which belong to the superfamily of GTPases. They cycle between an active GTP-bound state, formed from interaction with guanine nucleotide exchange factors (GEFs) such as Rabin8 and GRAB; and an inactive GDP-bound state via interaction with GTPase activating proteins (GAPs) such as TBC1D1. Rab8A activates various effector molecules, which are coupled to intracellular signaling networks that mediate membrane and vesicular trafficking, and actin remodeling. Rab8A is found in the golgi network, perinuclear region, plasma membrane, lamellipodia, and cilia, among other regions. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Detect Ras-related protein Rab-8A using this rabbit polyclonal antibody, Anti-RAB8A Antibody validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human RAB8A. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - RAB8
- RAB8A
- MEL
纯化方法 Antigen Affinity purified UniProt编号 - P61006
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected RAB8A in HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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