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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC394 描述 Anti-S1PR1 Antibody Alternate Names - S1PR1
- Sphingosine 1-phosphate receptor 1
- S1P receptor 1
- S1P1
- Endothelial differentiation G-protein coupled receptor 1
- Sphingosine 1-phosphate receptor Edg-1
- S1P receptor Edg-1
- CD363
背景信息 Sphingosine-1-phosphate receptor 1 (S1PR1, S1P1), also known as Endothelial differentiation G-protein coupled receptor 1 (EDG1, ECGF1), Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, is a bioactive lysophospholipid that evokes diverse physiological effects on most types of cells and tissues. Recent studies suggest that S1P1 promotes lymph node egression by overcoming retention signals mediated by CCR7 and G alpha i-protein-coupled receptor signaling. S1P1 may be involved in the processes that regulate the differentiation of endothelial cells. S1P1 is expressed highly in endothelial cells, and to a lesser extent in vascular smooth muscle cells, fibroblasts, melanocytes and cells of epithelioid origin. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-S1PR1 antibody detects level of S1PR1 & has been published & validated for use in S1PR1. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human S1PR1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Mouse Species Reactivity Note Mouse 抗体类型 Polyclonal Antibody 基因符号 - EDG1
- S1PR1
- CHEDG1
纯化方法 Antigen Affinity purified UniProt编号 - P21453
产品使用声明 质量保证 Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: A 1:600 dilution of this antibody detected S1PR1 in mouse brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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