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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H ICC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT182 描述 Anti-Nesprin-2 Antibody Alternate Names - Syne-2
- Nesprin-2
- Nuclear envelope spectrin repeat protein 2
- Nucleus and actin connecting element protein
- Protein NUANCE
- Synaptic nuclear envelope protein 2
背景信息 Nesprin-2 (SYNE-2) is also known as Nuclear envelope spectrin repeat protein 2 or Nucleus and actin connecting element protein, and it functions to network organelles and the actin cytoskeleton in order maintain subcellular spatial organization. Nesprin-2 connects nuclei to the cytoskeleton by interacting with the nuclear envelope and cytoplasmic F-actin, and is required for centrosome migration to the apical cell surface during early ciliogenesis. Nesprin-2 is widely expressed, with high levels seen in kidney, adult and fetal liver, stomach and placenta. Defects in SYNE2 are responsible for Emery-Dreifuss muscular dystrophy type 5 (EDMD5). 产品信息 格式 Affinity Purified 控制 - HeLa cells
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Nesprin-2 Antibody is a highly specific rabbit polyclonal antibody, that targets Nesprin-2 & has been tested in ICC & IHC (Paraffin). 主要应用 - Immunocytochemistry
应用说明 Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Nesprin-2 in human kidney and rat kidney (medulla and cortex) tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Nesprin-2. 表位 Cytoplasmic domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the cytoplasmic domain of Nesprin-2. 品种反应性 RatHuman Species Reactivity Note Demonstrated to react with Human and Rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_055995
基因符号 - NUA
- SYNE2
纯化方法 Affinity purified UniProt编号 - Q8WXH0
产品使用声明 质量保证 Evaluated by Immunocytochemistry in HeLa cells.
Immunocytochemistry Analysis: A 1:500 dilution of this antibody detected Nesprin-2 in HeLa cells使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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