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merck millipore,默克密理博,ABC159,Anti-MUC-1 Antibody, EC domain
产品名称：Anti-MUC-1 Antibody, EC domain
产品型号：ABC159
Detect MUC1 using this rabbit polyclonal antibody, Anti-MUC-1 Antibody, EC domain validated for use in western blotting & IHC (Paraffin).
merck millipore,默克密理博,ABC159,Anti-MUC-1 Antibody, EC domain
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC159 描述 Anti-MUC-1 Antibody, EC domain Alternate Names - CD227
- Mucin-1
- MUC-1
- Breast carcinoma-associated antigen DF3
- Carcinoma-associated mucin
- Episialin
- H23AG
- Krebs von den Lungen-6
- KL-6
- PEMT
- Peanut-reactive urinary mucin
- PUM
- Polymorphic epithelial mucin
- PEM
- Tumor-associated epithelial membrane antigen
- EMA
- Tumor-associated mucin
背景信息 MUC-1 (Mucin-1) is also known as Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, PEMT, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, and Tumor-associated mucin. The MUC-1 alpha subunit functions as protective layer on epithelial cells against bacteria and enzymes, and can act as both cell adhesion and an anti-adhesion protein. The beta subunit is involved in cell signaling in ERK, SRC and NF-kappa-B pathways, and the Ras/MAPK pathway in activated T-cells. MUC-1 also is involved in tumor progression and transcription through regulation of Tp53. MUC-1 is expressed in epithelial cells, breast, uterus, activated and unactivated T-cells and is overexpressed in epithelial tumors, such as breast or ovarian cancer. 产品信息 格式 Affinity Purified 控制 - Human serum
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect MUC1 using this rabbit polyclonal antibody, Anti-MUC-1 Antibody, EC domain validated for use in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: 0.1 µg/mL from a representative lot detected MUC-1, EC domain in 10 µg of human serum under reduced conditions.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected MUC-1, EC domain in normal human lung and human breast carcinoma tissues.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the extracellular domain of human MUC-1. 表位 Extracellular domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the extracellular domain of MUC-1. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001037858
基因符号 - PUM
- MUC1
纯化方法 Affinity purified UniProt编号 - P15941
产品使用声明 质量保证 Evaluated by Western Blotting in human serum.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected MUC-1, EC domain in 10 µg of human serum under non-reduced conditions.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 50 µg
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