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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Pm, H, R, Eq WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC150 描述 Anti-CXCR7 Antibody Alternate Names - RDC-1
- C-X-C chemokine receptor type 7
- CXC-R7
- CXCR-7
- Chemokine orphan receptor 1
- G-protein coupled receptor 159
- G-protein coupled receptor RDC1 homolog
背景信息 As a member of the G-protein coupled receptor 1 family, C-X-C chemokine receptor type 7 (CXCR7) serves as a receptor for chemokines CXCL12/SDF1 and CXL11 (I-TAC). Depending on the context, CXCR7 is observed to play multiple roles in cancer progression and survival, tumor invasion, cellular adhesion, ischemic stroke, and bone marrow HSC differentiation. CXCR7 activation results in beta-arrestin recruitment and subsequent MAPK signaling. Additionally, CXCR7 can exist as either a homodimer or heterodimerizes with CXCR4 to regulate CXCR4 signalling. 产品信息 格式 Affinity Purified 控制 - MCF7 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This CXCR7 antibody is validated for use in WB & IHC for the detection of the CXCR7 protein. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected CXCR7 in human kidney and distal renal tubule tissues.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected CXCR7 in rat kidney tissue.
Western Blot Analysis: 2 µg/mL from a representative lot detected CXCR7 in Jurkat cell lysate.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human CXCR7. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 PrimateHumanRatHorse Species Reactivity Note Demonstrated to react with Human and Rat. Predicted to react with Equine and Primate based on 100% sequence homology. Other homologies: Mouse (93% sequence homology) and Bovine (86% sequence homology). 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_064707
基因符号 - RDC1
- CXCR7
- CMKOR1
- GPR159
纯化方法 Affinity purified UniProt编号 - P25106
产品使用声明 质量保证 Evaluated by Western Blot in MCF7 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected CXCR7 in MCF7 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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