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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC10 描述 Anti-Megf10 Antibody Alternate Names - Multiple EGF-like domains protein 10
- Multiple epidermal growth factor-like domains protein 10
背景信息 Multiple epidermal growth factor-like domains protein 10 (Megf10) is a type 1 transmembrane protein with multiple EGF-like extracellular domains. Megf10 is highly expressed in the brain, and plays an important role in phacocytosis of apoptotic cells. This role may be performed through the interaction of Megf10 with the ATP-binding cassette transporter (ABCA1) protein. Previous studies have suggested that Megf10 may be involved in the uptake of amyloid β peptides in the brain. Megf10 may therefore play a role Alzheimer’s disease. 产品信息 格式 Affinity Purified 控制 - Mouse retina tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect the Megf10 protein using this Anti-Megf10 validated for use in WB & IF. 主要应用 - Western Blotting
应用说明 Immunofluorescence Analysis: A representative lot was used by an independent laboratory in P7 caudal brain tissue and retina cells. Image courtesy from the laboratory of Dr. Joshua Sanes, Harvard University. 生物信息 免疫原品种 Histidine-tagged recombinant protein corresponding to the cytoplasmic domain of mouse Megf10. 表位 Cytoplasmic domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes Megf10 at the cytoplasmic domain. 品种反应性 Mouse Species Reactivity Note Demonstrated to react with Mouse. Other homologies: Rat (98% sequence homology) and Human (92% sequence homology). 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001001979
基因符号 - Megf10
纯化方法 Affinity purified UniProt编号 - Q6DIB5
产品使用声明 质量保证 Evaluated by Western Blot in mouse retina tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Megf10 on 10 µg of mouse retina tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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