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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB Ch Purified Polyclonal Antibody 描述 产品目录编号 AB5735 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Neurofilament M Antibody 产品信息 格式 Purified 演示 Chicken IgY. Liquid containing ~5 mM sodium azide. 应用 应用 Anti-Neurofilament M Antibody detects level of Neurofilament M & has been published & validated for use in WB & IC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Western blot: 1:5,000-1:10,000
Immunocytochemistry: 1:1,000-1:2,000
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant C-terminal extension of rat NF-M, the so-called KE segment. 宿主 Chicken 特异性 Neurofilament M (NF-M) 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_005382.2
- NM_001105541.1
基因符号 - NFM
- NEFM
- NF-M
- NEF3
UniProt编号 - P07197
UniProt汇总 FUNCTION: SwissProt: P07197 # Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
SIZE: 916 amino acids; 102448 Da
PTM: There are a number of repeats of the tripeptide K-S-P, NFM is phosphorylated on a number of the serines in this motif. It is thought that phosphorylation of NFM results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. & Phosphorylation seems to play a major role in the functioning of the larger neurofilament polypeptides (NF-M and NF-H), the levels of phosphorylation being altered developmentally and coincident with a change in the neurofilament function.
SIMILARITY: SwissProt: P07197 ## Belongs to the intermediate filament family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µL
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