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  • merck millipore,默克密理博,AB5705,Anti-Calcitonin Gene Related Protein Antibody

  • merck millipore,默克密理博,AB5705,Anti-Calcitonin Gene Related Protein Antibody

    产品名称：Anti-Calcitonin Gene Related Protein Antibody
    产品型号：AB5705
    This Anti-Calcitonin Gene Related Protein Antibody is validated for use in IH for the detection of Calcitonin Gene Related Protein.

    merck millipore,默克密理博,AB5705,Anti-Calcitonin Gene Related Protein Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5705,Anti-Calcitonin Gene Related Protein Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RIHCChPurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5705
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Calcitonin Gene Related Protein Antibody
    Alternate Names
    • CGRP
    产品信息
    格式 Purified
    演示 Purified chicken IgY. Liquid containing 0.05% sodium azide.
    应用
    应用 This Anti-Calcitonin Gene Related Protein Antibody is validated for use in IH for the detection of Calcitonin Gene Related Protein.
    主要应用
    • Immunohistochemistry
    应用说明 Immunohistochemistry: 1:500 See Protocol below.

    Optimal working dilutions must be determined by the end user.



    AB5705 has been used successfully on perfusion fixed tissue. Perfusion: 1) Ca2+-free Tyrode's solution followed by 2) a paraformaldehyde-picric acid fixative and 3) 10% sucrose in PBS as a cryo-protectant. Tissues were rapidly dissected out and stored overnight in 0.1 M phosphate buffer (pH 7.4) containing 10% sucrose.Slide-mounted tissue sections were incubated with blocking buffer for 1 hour at room temperature. Primary antibody was diluted in blocking buffer to the appropriate working dilution. Blocking buffer was removed and the slides were then incubated at 2-8°C for 18-24 hours with AB5705. After rinsing in PBS 3 times sections were incubated for 60 minutes at room temperature with Cy3-conjugated secondary antibodies. After mounting in a mixture of PBS and glycerol (1:3) containing 0.1% p-phenylenediamine, sections were examined with a Nikon Microphot-SA epifluorescence microscope.
    生物信息
    免疫原品种 A 14 amino acid synthetic peptide from rat CGRP I (processed active peptide). The immunogen sequence is identical at 13 of 14 residues between rat/mouse CGRP I and CGRP II. {KDNFVPTNVGSEAF-NH2}
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Chicken
    特异性 CGRP (Calcitonin Gene Related Peptide).
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001741.2
    • NM_001033952.1
    • NM_001033953.1
    Entrez基因汇总 Calcitonin is a peptide hormone synthesized by the parafollicular cells of the thyroid. It causes reduction in serum calcium, an effect opposite to that of parathyroid hormone (PTH; MIM 168450).[supplied by OMIM]
    基因符号
    • CALC1
    • CGRP
    • MGC126648
    • calcitonin
    • CALCA
    • CGRP-I
    • KC
    • CT
    • CGRP1
    • katacalcin
    UniProt编号
    • P01258
    UniProt汇总 FUNCTION: SwissProt: P01258 # Katacalcin is a potent plasma calcium-lowering peptide.| P06881 # CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
    SIZE: 141 amino acids; 15467 Da
    SUBCELLULAR LOCATION: Secreted.
    DOMAIN: SwissProt: P01258
    SIMILARITY: SwissProt: P01258 ## Belongs to the calcitonin family.| P06881 ## Belongs to the calcitonin family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB5705,Anti-Calcitonin Gene Related Protein Antibody

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