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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB5687 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-FoxD3 Antibody Alternate Names - HNF-3
- Forkhead Box Protein D3
- Genesis
产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl containing 0.1% sodium azide. 应用 应用 Use Anti-FoxD3 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect FoxD3 also known as Forkhead Box Protein D3, Genesis, HNF-3, . 主要应用 - Western Blotting
应用说明 Western blot: 1-5 μg/mL using ECL. The antibody reacts with a protein of ~48 kDa on mouse ES cell lysate and TF-1 cell lysate. The antibody may also show reactivity to a ~30 kDa protein depending on sample used.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide from human FoxD3. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 FoxD3 (Forkhead box protein D3) 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_012183.2
Entrez基因汇总 This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined. 基因符号 - AIS1
- FOXD3
- HFH2
- Genesis
UniProt编号 - Q9UJU5
UniProt汇总 FUNCTION: SwissProt: Q9UJU5 # Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
SIZE: 478 amino acids; 47630 Da
SUBCELLULAR LOCATION: Nucleus (Probable).
TISSUE SPECIFICITY: Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.
SIMILARITY: SwissProt: Q9UJU5 ## Contains 1 fork-head DNA-binding domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. 包装信息 数量 100 µg
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