merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5561,Anti-GABA A Receptor β2 Antibody, cytoplasmic loop

  • merck millipore,默克密理博,AB5561,Anti-GABA A Receptor β2 Antibody, cytoplasmic loop

    产品名称：Anti-GABA A Receptor β2 Antibody, cytoplasmic loop
    产品型号：AB5561
    Anti-GABA A Receptor β2 Antibody, cytoplasmic loop is an antibody against GABA A Receptor β2 for use in IP & WB.

    merck millipore,默克密理博,AB5561,Anti-GABA A Receptor β2 Antibody, cytoplasmic loop

  • 产品介绍
  • merck millipore,默克密理博,AB5561,Anti-GABA A Receptor β2 Antibody, cytoplasmic loop

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, B, H, MWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5561
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-GABA A Receptor β2 Antibody, cytoplasmic loop
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. Approximate concentration is 0.2 mg/mL.
    应用
    应用 Anti-GABA A Receptor β2 Antibody, cytoplasmic loop is an antibody against GABA A Receptor β2 for use in IP & WB.
    主要应用
    • Western Blotting
    应用说明 Western blot: 1:1,000

    Immunopreciptation: The antibody will immunoprecipitate 68% of all GABAA receptors in dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 MBP fusion protein from the cytosolic loop of rat GABAA receptor beta2 subunit.
    表位 cytoplasmic loop
    宿主 Rabbit
    特异性 GABAA receptor beta2 subunit. The antibody is specific for the ~50 to 56kDa in rat brain membrane fractions.
    品种反应性 RatBovineHumanMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_021911.2
    • NM_000813.2
    Entrez基因汇总 The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.
    基因符号
    • MGC119388
    • GABRB2
    • MGC119386
    • GABA
    • MGC119389
    UniProt编号
    • P47870
    UniProt汇总 FUNCTION: SwissProt: P47870 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
    SIZE: 474 amino acids; 54606 Da
    SUBUNIT: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1.
    SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
    SIMILARITY: SwissProt: P47870 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB5561,Anti-GABA A Receptor β2 Antibody, cytoplasmic loop

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