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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M IHC, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB5400 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-GFR α3 Antibody 产品信息 格式 Serum 演示 Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue. 应用 应用 This Anti-GFR α3 Antibody is validated for use in WB, IH for the detection of GFR α3. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western blot: 1:500
Immunohistochemistry: 1:500-1:1,000
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 An eleven amino acid peptide corresponding to the N-terminus of the mouse GFR(3 protein. 宿主 Rabbit 特异性 GFRa3. No reactivity with its homologues. 品种反应性 Mouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001496.3
Entrez基因汇总 The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. 基因符号 - GFRa-3
- GFRA3
- ORFNames=UNQ339/PRO538/PRO3664
- GFR-alpha-3
UniProt编号 - O60609
UniProt汇总 FUNCTION: SwissProt: O60609 # Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.
SIZE: 400 amino acids; 44511 Da
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
TISSUE SPECIFICITY: Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression. Very low or no expression detected in the hematopoietic system.
PTM: N-glycosylated.
SIMILARITY: SwissProt: O60609 ## Belongs to the GDNFR family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain lyophilized material at -20°C to -70°C for up to 6 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µL
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下一件merck millipore产品：merck millipore,默克密理博,530050,PRIMA-1 - CAS 5608-24-2 - Calbiochem
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