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经验配方 CAS号 C₉H₁₅NO₃ 5608-24-2 描述 概述 A cell-permeable quinuclidinone analog with antitumor properties. Restores biochemical and biological function to mutant p53 and induces p53-dependent apoptosis in vitro and in vivo. Induces apoptosis in breast cancer cells expressing mutant p53. 产品目录编号 530050 品牌系列 Calbiochem®
同义词 2,2-Bis(hydroxymethyl)-1-azabicyclo[2,2,2]octan-3-one, p53 Reactivation and Induction of Massive Apoptosis 参考 参考 Bykov, V.J., et al. 2002. Nat. Med. 8, 282. 产品信息 CAS号 5608-24-2 具有ATP竞争性 N 形式 Off-white solid Hill配方 C₉H₁₅NO₃ 化学配方 C₉H₁₅NO₃ Molar Mass 185.2 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 Restores biochemical and biological function to mutant p53 纯度 ≥95% by NMR 理化信息 细胞可渗透 Y 溶解度 H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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