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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB5314 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Carboxypeptidase H Antibody, CT Alternate Names - Carboxypeptidase E
- CPH
产品信息 格式 Serum 演示 Serum with 0.02% sodium azide. 应用 应用 Anti-Carboxypeptidase H Antibody, C-terminus is an antibody against Carboxypeptidase H for use in IP, WB & IC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry on AtT-20 cell line: 1:100-1:500.
Western blot: 1:500-1:2,000. Carboxypeptidase H precursor migrates at 53 kDa while active enzyme migrates at about 48 kDa.
Immunoprecipitation: 1:250-1:1,000
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide corresponding to the C-terminus of Carboxypepdidase H conjugated to KLH. 表位 C-terminus 宿主 Rabbit 特异性 C-terminus of Carboxypepdidase H. 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001873.1
Entrez基因汇总 This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. 基因符号 - EC 3.4.17.10
- CPE
- CPH
UniProt编号 - P16870
UniProt汇总 FUNCTION: SwissProt: P16870 # Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.
COFACTOR: Binds 1 zinc ion per subunit (By similarity).
SIZE: 476 amino acids; 53151 Da
SUBCELLULAR LOCATION: Secreted. Note=Secretory granules of pancreatic islets, adrenal gland, pituitary and brain.
SIMILARITY: SwissProt: P16870 ## Belongs to the peptidase M14 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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