merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT379,Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1

  • merck millipore,默克密理博,MABT379,Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1

    产品名称：Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1
    产品型号：MABT379
    This Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1 is validated for use in western blotting & IHC for the detection of Anoctamin-1/TMEM16A.

    merck millipore,默克密理博,MABT379,Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1

  • 产品介绍
  • merck millipore,默克密理博,MABT379,Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT379
    描述 Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1
    Alternate Names
    • Tumor-amplified and overexpressed sequence 2
    • Anoctamin-1
    • Discovered on gastrointestinal stromal tumors protein 1
    • Oral cancer overexpressed protein 2
    • Transmembrane protein 16A
    背景信息 Discovered on gastrointestinal stromal tumors protein 1 (Dog1), also known as Anoctamin-1/TMEM16A, is a novel multi-pass membrane protein belonging to the anoctamin family. Anoctamin-1/TMEM16A functions as a Ca2+-activated Cl- channel and is a required component of tracheal development. Expression of Anoctamin-1/TMEM16A is elevated in the gastrointestinal stromal tumors (GISTs), KIT signaling-driven mesenchymal tumors of the GI tract. It is also expressed at more moderate levels in epithelia from foregut, kidney, lung, pancreas and salivary glands. Recent studies suggest that it may serve a roll as a diagnostic marker in the classification of GISTs.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1 is validated for use in western blotting & IHC for the detection of Anoctamin-1/TMEM16A.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Anoctamin-1/TMEM16A in human prostate cancer sections.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to the N-terminal cytoplasmic domain of human Anoctamin-1/TMEM16A.
    表位 N-terminal cytoplasmic domain
    克隆 5F8.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody recognizes isoforms 1 and 2 of Anoctamin-1 based upon immunogen design.
    同种型 IgG1κ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_060513
    基因符号
    • TAOS2
    • ANO1
    • DOG1
    • ORAOV2
    纯化方法 Protein G purified
    UniProt编号
    • Q5XXA6
    产品使用声明
    质量保证 Evaluated by Western Blotting in PC-3 cell lysate.

    Western Blotting Analysis: 1 µg/mL of this antibody detected Anoctamin-1/TMEM16A in 10 µg of PC-3 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABT379,Anti-Anoctamin-1/TMEM16A Antibody, clone 5F8.1

上一件merck millipore产品：merck millipore,默克密理博,SF-1392,ASXL1; Human, Cyanine 3 RNA Detection Probe,SmartFlare
下一件merck millipore产品：merck millipore,默克密理博,SF-3320,ELK; Human, Cyanine 5 RNA Detection Probe,SmartFlare


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