merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5066P,Anti-Norepinephrine Transporter Antibody

  • merck millipore,默克密理博,AB5066P,Anti-Norepinephrine Transporter Antibody

    产品名称：Anti-Norepinephrine Transporter Antibody
    产品型号：AB5066P
    This Anti-Norepinephrine Transporter Antibody is validated for use in ELISA, WB for the detection of Norepinephrine Transporter.

    merck millipore,默克密理博,AB5066P,Anti-Norepinephrine Transporter Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5066P,Anti-Norepinephrine Transporter Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, MWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5066P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Norepinephrine Transporter Antibody
    Alternate Names
    • NET
    产品信息
    格式 Affinity Purified
    控制
    • Brain tissue
    演示 Affinity Purified immunoglobulin. Liquid in PBS with 0.1% BSA .
    应用
    应用 This Anti-Norepinephrine Transporter Antibody is validated for use in ELISA, WB for the detection of Norepinephrine Transporter.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-10 μg/mL (Chemiluminescence technique): NET can exist is at least two forms, a highly glycosylated ~80kDa form is the most common in brain, and a lessly glycosylated 54kDa form is also seen in some regions and tissues.



    ELISA: 1:10,000-1:100,000 (50-100 ng immunogen peptide/well) Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 22 amino acid peptide sequence mapping to the 1st extracellular domain of rat NET.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Specific for Norepinephrine Transporter (NET). Norepinephrine Transporter is a 617 amino acid long integral membrane protein belonging to the Sodium:Neurotransmitter Symporter family (Bruss et al. 1995; Melikian et al. 1994; Pacholczyk et al. 1991) The immunogen peptide shows no significant homology with other other known proteins.
    品种反应性 RatMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001043.2
    Entrez基因汇总 The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis (Kim et al., 2006 [PubMed 17146058]).[supplied by OMIM]
    基因符号
    • NET1
    • SLC6A2
    • NAT1
    • NET
    • SLC6A5
    纯化方法 Immunoaffinity purified
    UniProt编号
    • P23975
    UniProt汇总 FUNCTION: SwissProt: P23975 # Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
    SIZE: 617 amino acids; 69332 Da
    SUBUNIT: Interacts with PRKCABP.
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    DISEASE: SwissProt: P23975 # Defects in SLC6A2 are a cause of orthostatic intolerance (OI) [MIM:604715]. OI is a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high.
    SIMILARITY: SwissProt: P23975 ## Belongs to the sodium:neurotransmitter symporter (SNF) family.
    MISCELLANEOUS: This protein is the target of psychomotor stimulants such as amphetamines or cocaine.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB5066P,Anti-Norepinephrine Transporter Antibody

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