merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5042,Anti-Choline Acetyltransferase Antibody

  • merck millipore,默克密理博,AB5042,Anti-Choline Acetyltransferase Antibody

    产品名称：Anti-Choline Acetyltransferase Antibody
    产品型号：AB5042
    Detect Choline Acetyltransferase using this Anti-Choline Acetyltransferase Antibody validated for use in IH.

    merck millipore,默克密理博,AB5042,Anti-Choline Acetyltransferase Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5042,Anti-Choline Acetyltransferase Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, Av, GpIHCRbSerumPolyclonal Antibody
    描述
    产品目录编号 AB5042
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Choline Acetyltransferase Antibody
    Alternate Names
    • ChAT
    产品信息
    格式 Serum
    演示 Lyophilized. Reconstitute with 100 μL of sterile distilled water. Contains no preservative.
    应用
    应用 Detect Choline Acetyltransferase using this Anti-Choline Acetyltransferase Antibody validated for use in IH.
    主要应用
    • Immunohistochemistry
    应用说明 Immunohistochemistry: 1:2,000-1:4,000 in rat basal forebrain.

    Western blot

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 22 amino acid synthetic peptide from porcine ChAT, coupled to KLH. The peptide sequence is GLFSSYRLPGHTQDTLVAQKSS. Due to sequence similarity, the antibody is expected to react with pig, rat, mouse and human ChAT.
    宿主 Rabbit
    特异性 Will stain cholinergic neurons in rat central and peripheral nervous systems.
    品种反应性 RatAvianGuinea Pig
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_020986.2
    • NM_020549.3
    • NM_020984.2
    • NM_020985.2
    Entrez基因汇总 Cholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein.
    基因符号
    • EC 2.3.1.6
    • CHAT
    • ChAT
    • CMS1A2
    • CHOACTase
    • CMS1A
    UniProt编号
    • P28329
    UniProt汇总 FUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
    SIZE: 748 amino acids; 82568 Da
    DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.
    SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material dry at -20°C or -70°C for up to 6 months after date of receipt. After reconstitution, maintain at -20°C in undiluted aliquots for up to 6 months. Glycerol (1:1) can be added for additional stability.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB5042,Anti-Choline Acetyltransferase Antibody

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