merck millipore,默克密理愽
  • merck millipore,默克密理博,422625,KLF5 Inhibitor, CID 5951923 - CAS 749872-43-3 - Calbiochem

  • merck millipore,默克密理博,422625,KLF5 Inhibitor, CID 5951923 - CAS 749872-43-3 - Calbiochem

    产品名称：KLF5 Inhibitor, CID 5951923 - CAS 749872-43-3 - Calbiochem
    产品型号：422625
    The KLF5 Inhibitor, CID 5951923 controls the biological activity of KLF5.

    merck millipore,默克密理博,422625,KLF5 Inhibitor, CID 5951923 - CAS 749872-43-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,422625,KLF5 Inhibitor, CID 5951923 - CAS 749872-43-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₈N₂O₇S749872-43-3
    描述
    概述 A cell-permeable phenylpropenoate compound that inhibits the proliferation of colon cancer cell lines exhibiting high levels of KLF5 (IC50 = 1.6 µM in DLD-1 cells). Downregulates the expression of early growth response protein 1 (EGR1), which modulates KLF5 expression at transcription level. Shown to activate the EGFR/ERK pathway by stimulating phosphorylation of EGFR-Tyr1068 and ERK1/2-Thr202/Tyr204. Also, up-regulates the phosphorylation of p38 MAPK-Thr180/Tyr182.
    产品目录编号 422625
    品牌系列 Calbiochem®
    同义词 2-((1,1-Dioxidotetrahydrothiophen-3-yl)(methyl)amino)-2-oxoethyl-(2E)-3-(3-nitrophenyl)prop-2-enoate
    参考
    参考 Bialkowska, A., et al. 2011. Mol. Cancer Ther. 10, 2043.
    产品信息
    CAS号 749872-43-3
    形式 Off-white solid
    Hill配方 C₁₆H₁₈N₂O₇S
    化学配方 C₁₆H₁₈N₂O₇S
    Molar Mass 382.4
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock Solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,422625,KLF5 Inhibitor, CID 5951923 - CAS 749872-43-3 - Calbiochem

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