merck millipore,默克密理愽
  • merck millipore,默克密理博,AB3316P,Anti-Monocarboxylate Transporter 4 Antibody

  • merck millipore,默克密理博,AB3316P,Anti-Monocarboxylate Transporter 4 Antibody

    产品名称：Anti-Monocarboxylate Transporter 4 Antibody
    产品型号：AB3316P
    Anti-Monocarboxylate Transporter 4 Antibody detects level of Monocarboxylate Transporter 4 & has been published & validated for use in ELISA & WB.

    merck millipore,默克密理博,AB3316P,Anti-Monocarboxylate Transporter 4 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB3316P,Anti-Monocarboxylate Transporter 4 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB3316P
    Replaces AB3548P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Monocarboxylate Transporter 4 Antibody
    Alternate Names
    • MCT4
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.
    应用
    应用 Anti-Monocarboxylate Transporter 4 Antibody detects level of Monocarboxylate Transporter 4 & has been published & validated for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-5 μg/mL using ECL.
    Immunohistochemistry: Not tested. Recommended antibody testing dilution: 5-10 μg/mL on paraformaldehyde fixed tissue.
    ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog number AG219) per well.
    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 19 amino acid peptide sequence within the cytoplasmic domain #4 of human MCT4 (Wilson et al., 1998; Price et al., 1998).
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes human Monocarboxylate Transporter 4 (MCT4). The immunogen shows no significant sequence homology with other MCT. MCT4 is prominently expressed in skeletal muscle and other cells with high glycolytic rate such as tumors cells and white blood cells suggesting an important role in lactic acid efflux.

    Note: According to new nomenclature, the old MCT3 has now been reclassified as MCT4. Consult Halestrap and Price (1999) Biochem. J. 343:281-299.
    品种反应性 Human
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_004207.2
    • NM_001042422.1
    • NM_001042423.1
    Entrez基因汇总 Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM]
    基因符号
    • MCT4
    • SLC16A3
    • MCT3
    • MGC138472
    • MGC138474
    UniProt编号
    • O15427
    UniProt汇总 FUNCTION: SwissProt: O15427 # Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
    SIZE: 465 amino acids; 49469 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Highly expressed in skeletal muscle.
    SIMILARITY: SwissProt: O15427 ## Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB3316P,Anti-Monocarboxylate Transporter 4 Antibody

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