merck millipore,默克密理愽
  • merck millipore,默克密理博,AB3264,Anti-K+/Cl- Cotransporter 2b Antibody, pain, NT

  • merck millipore,默克密理博,AB3264,Anti-K+/Cl- Cotransporter 2b Antibody, pain, NT

    产品名称：Anti-K+/Cl- Cotransporter 2b Antibody, pain, NT
    产品型号：AB3264
    Anti-K+/Cl-Cotransporter 2b Antibody, pain, N-terminus is an antibody against K+/Cl-Cotransporter 2b for use in ELISA & WB.

    merck millipore,默克密理博,AB3264,Anti-K+/Cl- Cotransporter 2b Antibody, pain, NT

  • 产品介绍
  • merck millipore,默克密理博,AB3264,Anti-K+/Cl- Cotransporter 2b Antibody, pain, NT

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB3264
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-K+/Cl- Cotransporter 2b Antibody, pain, NT
    Alternate Names
    • Solute Carrier Family 12 Member 5
    • KCC2
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in phosphate buffered saline, pH 7.4, containing 0.1% BSA and 0.1% sodium azide.
    应用
    应用 Anti-K+/Cl-Cotransporter 2b Antibody, pain, N-terminus is an antibody against K+/Cl-Cotransporter 2b for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-10 μg/mL using ECL.Approximate size on reduced westerns is 140-145kDa; membrane preparations and proteinase inhibitors are strongly recommended.

    ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 An 18 amino acid peptide within the cytoplasmic, N-terminus of rat KCC2b.
    表位 N-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes K+ Cl- Cotransporter-2 (KCC2b). The immunogen shows no significant sequence homology with other KCCs or CCC. AB3264 is specific for KCC2b and will not detect KCC2a.

    SPECIES REACTIVITIES: The immunogen sequence is 100% conserved in mouse. Reactivity with other species has not been confirmed.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_020708.3
    Entrez基因汇总 K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons.
    基因符号
    • hKCC2
    • SLC12A5
    • KIAA1176
    • KCC2
    UniProt编号
    • Q9H2X9
    UniProt汇总 FUNCTION: SwissProt: Q9H2X9 # Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
    SIZE: 1139 amino acids; 126184 Da
    SUBUNIT: Homomultimer and heteromultimer with other K-Cl cotransporters (By similarity).
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Brain specific. Detected in neuronal cells.
    SIMILARITY: SwissProt: Q9H2X9 ## Belongs to the SLC12A transporter family.
    MISCELLANEOUS: Inhibited by furosemide and bumetanide.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

    During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial on a tabletop centrifuge to dislodge any liquid in the container's cap.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB3264,Anti-K+/Cl- Cotransporter 2b Antibody, pain, NT

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