merck millipore,默克密理愽
  • merck millipore,默克密理博,555554,Rho Kinase Inhibitor IV - Calbiochem

  • merck millipore,默克密理博,555554,Rho Kinase Inhibitor IV - Calbiochem

    产品名称：Rho Kinase Inhibitor IV - Calbiochem
    产品型号：555554
    The Rho Kinase Inhibitor IV controls the biological activity of Rho Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,555554,Rho Kinase Inhibitor IV - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,555554,Rho Kinase Inhibitor IV - Calbiochem

    重要规格表

    经验配方
    C₁₈H₂₄N₄O₃S • 2HCl • H₂O
    描述
    概述 A cell-permeable, reversible, and ATP-comptetive glycyl analog of Rho-Kinase Inhibitor (Cat. No. 555550) that inhibits ROCK with an improved selectivity (IC50 = 11.8 nM, > 10 µM, > 10 µM, 3.26 µM, 2.35 µM, and 2.57 µM for ROCKII, PKA, PKC, PKG, Aurora A, and CaMKII, respectively).
    产品目录编号 555554
    品牌系列 Calbiochem®
    同义词 (S)-(+)-2-Methyl-4-glycyl-1-(4-methylisoquinolinyl-5-sulfonyl)homopiperazine, 2HCl, H-1152, Glycyl
    参考
    参考 Tamura, M., et al. 2005. Biochim. Biophys. Acta, 1754, 245.
    产品信息
    具有ATP竞争性 Y
    形式 Pale yellow solid
    Hill配方 C₁₈H₂₄N₄O₃S • 2HCl • H₂O
    化学配方 C₁₈H₂₄N₄O₃S • 2HCl • H₂O
    Molar Mass 467.4
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 ROCK II
    主靶IC50 11.8 nM against ROCK II
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or H₂O
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Harmful
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,555554,Rho Kinase Inhibitor IV - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,HTS099RTA,Ready-to-Assay™ EP1 Prostanoid Receptor Frozen Cells
下一件merck millipore产品：merck millipore,默克密理博,178281,p-APMSF, Hydrochloride - CAS 74938-88-8 - Calbiochem


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