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  • merck millipore,默克密理博,AB3152,Anti-Amphiregulin Antibody

  • merck millipore,默克密理博,AB3152,Anti-Amphiregulin Antibody

    产品名称：Anti-Amphiregulin Antibody
    产品型号：AB3152
    This Anti-Amphiregulin Antibody is validated for use in ELISA, IP, WB for the detection of Amphiregulin.

    merck millipore,默克密理博,AB3152,Anti-Amphiregulin Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB3152,Anti-Amphiregulin Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HWB, ELISARbPurifiedPolyclonal Antibody
    描述
    产品目录编号 AB3152
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Amphiregulin Antibody
    Alternate Names
    • KAF
    • AR
    • CRDGF
    产品信息
    格式 Purified
    演示 Purified immunoglobulin from rabbit anti-serum by Protein A chromatography. Liquid in 10mM PBS, pH 7.4, with 0.2% BSA and 15mM sodium azide.
    应用
    应用 This Anti-Amphiregulin Antibody is validated for use in ELISA, IP, WB for the detection of Amphiregulin.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Immunoprecipitation (Use Protein A): Ab 10μg/mg protein lysate.

    Western Blotting: Ab 5μg/ml for 2hrs at room temperature.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 A synthetic 19-mer peptide, corresponding to aa 26-44 from the secreted amphiregulin of human origin.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes a glycoprotein of 18.5-22.5kDa, identified as amphiregulin (AR). Antibody is directed against the region of AR, which binds to heparin and is highly specific to AR. It shows no cross-reaction with EGF, TGFalpha, or HB-EGF. In vitro, AR functions as an autocrine growth stimulator to derive proliferation of colon carcinoma cells, normal and oncogene-transformed mammary epithelial cells, cervical carcinoma cells, prostate cancer cells, and keratinocytes. AR is important in development of human placenta and murine mammary gland.
    品种反应性 MouseHuman
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001657.2
    Entrez基因汇总 The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
    基因符号
    • SDGF
    • AREG
    • MGC13647
    • CRDGF
    • amphiregulin
    • AR
    UniProt编号
    • P15514
    UniProt汇总 FUNCTION: SwissProt: P15514 # Bifunctional growth-modulating glycoprotein. Inhibits growth of several human carcinoma cells in culture and stimulates proliferation of human fibroblasts and certain other tumor cells.
    SIZE: 252 amino acids; 27895 Da
    SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein.
    SIMILARITY: SwissProt: P15514 ## Belongs to the amphiregulin family. & Contains 1 EGF-like domain.
    MISCELLANEOUS: AR is a protein containing cysteines in disulfide linkage(s) that are essential for its biological activity. AR may contain oligosaccharides and/or lipid moieties that are not obligatory for the biological activity.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB3152,Anti-Amphiregulin Antibody

上一件merck millipore产品：merck millipore,默克密理博,05-23-2150,PACAP 38, Ovine - CAS 137061-48-4 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,MMADD651,HepaRG™ Serum Free Induction Medium Supplement


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