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merck millipore,默克密理博,AB3000,Anti-IP3 Receptor Type II Antibody
产品名称：Anti-IP3 Receptor Type II Antibody
产品型号：AB3000
Anti-IP3 Receptor Type II Antibody detects level of IP3 Receptor Type II & has been published & validated for use in IC, IF, IH, IP & WB.
merck millipore,默克密理博,AB3000,Anti-IP3 Receptor Type II Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, Ht, M, Mk WB, ICC, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB3000 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-IP3 Receptor Type II Antibody Alternate Names - Inositol 1,4,5-Trisphosphate Receptor
产品信息 格式 Affinity Purified 演示 Affinity purified versus immobilized immunogen peptide. Liquid in PBS buffer, containing 0.05% BSA, 10% glycerol, 0.005% sodium azide. Caution: Sodium azide is hazardous. MSDS available upon request. 应用 应用 Anti-IP3 Receptor Type II Antibody detects level of IP3 Receptor Type II & has been published & validated for use in IC, IF, IH, IP & WB. 主要应用 - Western Blotting
- Immunocytochemistry
- Immunohistochemistry
应用说明 Western blot: 1:50 - 1:100 (detects a 260 kDa band)
Immunofluorescence: 1:10 - 1:20
Immunoprecipitation
Immunocytochemistry: Known to give positive reactivity on AR4-2J, HL-60, COS-I, HEK-293, and RBL-2H3 cell lines.
Immunohistochemistry: Paraformaldehyde or methanol fixes are effective.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor 宿主 Rabbit 特异性 Rabbit anti-Type II Inositol 1,4,5-Trisphosphate Receptor (IP3R) is directed against a synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor. The antibody is reactive with Type II IP3R from rat, mouse, human, hamster, and monkey. 品种反应性 RatHumanHamsterMouseMonkey 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_002223.2
基因符号 - IP3R2
- ITPR2
- InsP3R2
UniProt编号 - Q14571
UniProt汇总 FUNCTION: SwissProt: Q14571 # Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
SIZE: 2701 amino acids; 308078 Da
SUBUNIT: Homotetramer (By similarity).
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: The short isoform is found in skeletal muscle and heart.
DOMAIN: SwissProt: Q14571 The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand- binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.
PTM: Phosphorylated on tyrosine residues (By similarity).
SIMILARITY: Belongs to the InsP3 receptor family. & Contains 5 MIR domains.
MISCELLANEOUS: Calcium appears to inhibit ligand binding to the receptor, most probably by interacting with a distinct calcium- binding protein which then inhibits the receptor.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 12 months. 包装信息 数量 50 µL
上一件merck millipore产品：merck millipore,默克密理博,220486,Chk2 Inhibitor II - CAS 516480-79-8 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,AB9826-200UL,Anti-Cav3.2 Antibody
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