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品种反应性 主要应用 宿主 格式 抗体类型 Rhesus Macaque, H, M, R ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB2971 描述 Anti-LAMP-1 (CD107a) Antibody Alternate Names - CD107a antigen
- lysosomal-associated membrane protein 1
- lysosome-associated membrane glycoprotein 1
- Lysosome-associated membrane protein 1
- CD107 antigen-like family member A
背景信息 Lysosome-associated membrane protein 1 (LAMP-1) is a highly glycosolated, single-pass type 1 membrane protein belonging to the lysosome- associated membrane protein family; a group of proteins that make up the majority of the lysosomal membrane and are considered crucial mediators for cellular adhesion by interacting with carbohydrate receptors. LAMP-1 functions to traffic carbohydrate ligands to selectins. It is also thought to play a role in tumor cell metastasis. 产品信息 格式 Affinity Purified 控制 - EL4 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-LAMP-1 (CD107a) Antibody is validated for use in WB, IC for the detection of LAMP-1 (CD107a). 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Western Blot (Snap i.d.) Analysis: 1 µg/mL from a previous lot detected LAMP-1 in 10 µg of EL4 cell lysate.
Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected LAMP-1 in NIH/3T3, A431, and HeLa cells.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human LAMP-1 at the topological domain (Lumenal). 表位 Topological domain (Lumenal) 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 The antibody recognizes LAMP-1 at the topological domain (Lumenal). 品种反应性 Rhesus MacaqueHumanMouseRat Species Reactivity Note Demonstrated to react with human, mouse, and rat. Predicted to react with rhesus macaque based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005552
Entrez基因汇总 The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq]. 基因符号 - CD107a
- LAMP1
- LAMP-1
- LAMPA
- LGP120
纯化方法 Affinity purified UniProt编号 - P11279
UniProt汇总 FUNCTION: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note: This protein shuttles between lysosomes, endosomes, and the plasma membrane.
PTM: O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.
SEQUENCE SIMILARITIES: Belongs to the LAMP family.产品使用声明 质量保证 Evaluated by Western Blot in EL4 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected LAMP-1 in 10 µg of EL4 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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