merck millipore,默克密理愽
  • merck millipore,默克密理博,AB2232,Anti-Atrial Natriuretic Polypetide Antibody, alpha

  • merck millipore,默克密理博,AB2232,Anti-Atrial Natriuretic Polypetide Antibody, alpha

    产品名称：Anti-Atrial Natriuretic Polypetide Antibody, alpha
    产品型号：AB2232
    This Anti-Atrial Natriuretic Polypetide Antibody, alpha is validated for use in WB for the detection of Atrial Natriuretic Polypetide.

    merck millipore,默克密理博,AB2232,Anti-Atrial Natriuretic Polypetide Antibody, alpha

  • 产品介绍
  • merck millipore,默克密理博,AB2232,Anti-Atrial Natriuretic Polypetide Antibody, alpha

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 AB2232
    描述 Anti-Atrial Natriuretic Polypetide Antibody, alpha
    Alternate Names
    • natriuretic peptide precursor A variant 2
    • Atrial natriuretic peptide
    • natriuretic peptide precursor A
    背景信息 Atrial natriuretic polypeptide, alpha (ANP), atrial natriuretic factor (ANF), or atriopeptin, is a protein (polypeptide) hormone secreted by heart muscle cells. It is involved in the homeostatic control of body water, sodium, potassium and fat (adiposity). It is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes), in response to high blood pressure. ANP acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure. ANP binds to a specific set of receptors - ANP receptors. Receptor-agonist binding causes a reduction in blood volume and therefore a reduction in cardiac output and systemic blood pressure. Lipolysis is increased and renal sodium reabsorption is decreased. The overall effect of ANP on the body is to counter increases in blood pressure and volume caused by the renin-angiotensin system (1).
    产品信息
    格式 Purified
    控制
    • Rat Heart
    演示 Purified in 0.1M Tris-Glycine (pH7.4) 15mM NaCl with 0.05% NaN3
    应用
    应用 This Anti-Atrial Natriuretic Polypetide Antibody, alpha is validated for use in WB for the detection of Atrial Natriuretic Polypetide.
    主要应用
    • Western Blotting
    应用说明 Non-Lot Specific Tested Application 1:
    Immunohistochemistry:
    1:50-1:500 on paraffin embedded tissue.

    Optimum dilutions need to be determined by the end user.
    生物信息
    免疫原品种 Synthetic Linear Peptide
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Cat. # AB2232 recognizes ANP, alpha
    品种反应性 RatHumanMouse
    Species Reactivity Note Rat, Human and Mouse. May react with dog, cat and cow based on sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_006163.1
    基因符号
    • pronatriodilatin
    • ANF
    • ANP
    • CDD-ANF
    • OTTHUMP00000002504
    • OTTHUMP00000044485
    • PND
    • Prepronatriodilatin
    纯化方法 Purified
    UniProt编号
    • P01160
    UniProt汇总 FUNCTION: A potent vasoactive substance which is thought to play a key role in cardiovascular homeostasis. Has a cGMP-stimulating activity.
    SUBUNIT: Interacts with NPR3.
    LOCATION: Secreted.
    POLYMORPHISM: There are two different prepronatriodilatin alleles. One codes for 2 Arg residues at the C-terminus that are cleaved to form the mature peptide, while the other ends in a termination codon immediately after the last codon of the mature peptide.
    SIMILARITY: Belongs to the natriuretic peptide family.
    产品使用声明
    质量保证 Routinely evaluated by western blot
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    Handling Recommendations: Prior to removing the cap, gently centrifuge the vial and gently mix the solution.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB2232,Anti-Atrial Natriuretic Polypetide Antibody, alpha

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