- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M IHC, WB, ICC Rb Serum Polyclonal Antibody 描述 产品目录编号 AB2209 描述 Anti-ABBA Antibody Alternate Names - actin-bundling protein with BAIAP2 homology
背景信息 Radial glia play key roles in neuronal migration, axon guidance, and neurogenesis during development of the central nervous system. However, the molecular mechanisms regulating growth and morphology of these extended cells are unknown. ABBA, a novel member of the IRSp53/MIM protein family, is enriched in different types of radial glia. ABBA binds ATP-actin monomers with high affinity and deforms PIP2-rich membranes in vitro through its WH2 and IMdomains, respectively. In radial glia-like C6-R cells, ABBA localizes to the interface between the actin cytoskeleton and plasma membrane, and its depletion by RNAi leads to defects in lamellipodial dynamics and process extension. Together, ABBA acts as a novel regulator of actin and plasma membrane dynamics in radial glial cells, and provides evidence that the membrane binding/deformation activity is critical for the cellular functions of IRSp53/MIM/ABBA family proteins 产品信息 格式 Serum 控制 - Mouse brain lysate
演示 Serum with with 0.05% NaN3 应用 应用 Anti-ABBA Antibody is an antibody against ABBA for use in WB, IC, IH. 主要应用 - Immunohistochemistry
- Western Blotting
- Immunocytochemistry
应用说明 Non-Lot Specific Tested Application 1:
Immunocytochemistry: 1:50 dilution in mouse primary glial cell line and C6, C6-R rat cell line.
Non-Lot Specific Tested Application 2:
Immunohistochemistry: 1:1,000 in embryonic and adult brain tissue.
(See Reference for more information)
生物信息 免疫原品种 Recombinant protein. 宿主 Rabbit 特异性 Cat. # AB2209 recognizes ABBA 品种反应性 RatHumanMouse Species Reactivity Note Human, Mouse and Rat. May react with Pan troglodytes and Macaca mulatta based on sequence homology. Reactivity with other species was not tested. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_941027
基因符号 - ABBA
- MGC79213
UniProt编号 - Q6P9S0
产品使用声明 质量保证 Routinely tested on mouse brain lysate
Lot Specific Tested Application 1: Western Blot
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,234378,Macrophage Colony-Stimulating Factor, Mouse, Recombinant, E. coli
下一件merck millipore产品：merck millipore,默克密理博,AB5895,Anti-P2X3 Receptor Antibody, pain
相关产品
merck millipore,默克密理博,559393,SB 202190, Hydrochloride - CAS 350228-36-3 - Calbiochem
merck millipore,默克密理博,05-923,Anti-XPG Antibody, clone 8H7
merck millipore,默克密理博,ABT34,Anti-Podoplanin Antibody
merck millipore,默克密理博,07-448-S,Anti-monomethyl-Histone H3 (Lys27) Antibody, Trial Size
merck millipore,默克密理博,234378,Macrophage Colony-Stimulating Factor, Mouse, Recombinant, E. coli
merck millipore,默克密理博,AB5895,Anti-P2X3 Receptor Antibody, pain
merck millipore,默克密理博,346125,D-Gluconic Acid, Potassium Salt - CAS 299-27-4 - Calbiochem
merck millipore,默克密理博,AB1963,Anti-N-WASP Antibody
merck millipore,默克密理博,CBL270,Anti-Tubulin Antibody, clone YOL 1/34
merck millipore,默克密理博,05-253MG,Anti-ZAP-70 Antibody, clone 2F3.2