- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,AB1892,Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, NT
产品名称：Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, NT
产品型号：AB1892
Detect C-X-X-X-C Chemokine Receptor 1 using this Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, N-terminus validated for use in IH & WB.
merck millipore,默克密理博,AB1892,Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, NT
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB, IHC Rb Purified Polyclonal Antibody 描述 产品目录编号 AB1892 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, NT Alternate Names - CX3CR1
背景信息 CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively (1-4). The seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by facktokine (6). CX3CR1 mediates leukocyte migration and adhesion. 产品信息 格式 Purified 演示 Purified immunoglobulin. 100 μg purified IgG in 100 μL of PBS containing 0.2% sodium azide. 应用 应用 Detect C-X-X-X-C Chemokine Receptor 1 using this Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, N-terminus validated for use in IH & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Western blot: 1:500 - 1:2000 (Human spleen tissue lysate can be used as positive control and an approximately 50 kDa band can be detected)
Immunohistochemistry in frozen sections
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide from the N-terminal of human CX3CR1. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Specific for human C-X-X-X-C Chemokine Receptor 1 (CX3CR1) at the Extracellular loop. The sequence is identical to that of rat and differs from that of mouse by only one amino acid. 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001337.3
基因符号 - CMKBLR1
- CX3CR1
- CMKDR1
- GPR13
- CMK-BRL-1
- V28
- GPRV28
- CMKBRL1
- CCRL1
UniProt编号 - P49238
UniProt汇总 FUNCTION: SwissProt: P49238 # Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV coreceptors than isoform 1.
SIZE: 355 amino acids; 40396 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in lymphoid and neural tissues.
SIMILARITY: SwissProt: P49238 ## Belongs to the G-protein coupled receptor 1 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at 2-8°C for up to 12 months. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,07-611,Anti-Peroxiredoxin 3 Antibody
下一件merck millipore产品：merck millipore,默克密理博,567021,Simvastatin, Sodium Salt - Calbiochem
相关产品
merck millipore,默克密理博,BG-8-C,Beta-Galactosidase Tissue Stain Base Solution
merck millipore,默克密理博,AB15708,Anti-β III tubulin Antibody
merck millipore,默克密理博,AB9698,Anti-Neuron Specific Enolase (NSE) Antibody
merck millipore,默克密理博,MAB411,Anti-Interferon-α Antibody, clone ST10,29,225,254
merck millipore,默克密理博,07-611,Anti-Peroxiredoxin 3 Antibody
merck millipore,默克密理博,567021,Simvastatin, Sodium Salt - Calbiochem
merck millipore,默克密理博,AB15115,Anti-NARC-1 Antibody
merck millipore,默克密理博,AG952,Tau-381, recombinant human
merck millipore,默克密理博,MABE370,Anti-Thymidylate Synthase-5FU complex Antibody, clone FTS
