merck millipore,默克密理博,AB15882,Anti-HuC Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H, R	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	AB15882
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-HuC Antibody
背景信息	Hu proteins are mammalian embryonic lethal abnormal visual system (ELAV)-like neuronal RNA-binding proteins that contain three RNA recognition motifs. RNA binding protein HuC promotes neuronal development in both the central and the peripheral nervous systems. HuC antibodies are are also used as markers for developing neurons.

产品信息
格式	Affinity Purified
控制	Tested on adult rat brain lysate
演示	Purified Antibody in PBS with 0.1% NaN3

应用
应用	Anti-HuC Antibody detects level of HuC & has been published & validated for use in WB.
主要应用	Western Blotting

生物信息
免疫原品种	Synthetic peptide near the N-terminus human/rat/mouse HuC.
表位	N-Terminus
宿主	Rabbit
特异性	HuC. By Western blot the antibody reacts with a band at ~ 39 kDa on adult rat brain lysate and rat spinal cord lysate. An additional band at ~ 25 kDa may be seen depending on sample and antibody concentration used.
品种反应性	HumanRat
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_032281.2 NM_001420.3
Entrez基因汇总	A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
基因符号	DKFZp547J036 ELAVL3 PLE21 HUCL MGC20653 HUC HuC
纯化方法	Immunoaffinity purified
UniProt编号	Q14576
UniProt汇总	FUNCTION: SwissProt: Q14576 # May be involved in neuronal differentiation and maintenance. SIZE: 367 amino acids; 39547 Da TISSUE SPECIFICITY: Brain specific. SIMILARITY: SwissProt: Q14576 ## Belongs to the RRM elav family. & Contains 3 RRM (RNA recognition motif) domains.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,AB15882,Anti-HuC Antibody

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