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品种反应性 主要应用 宿主 抗体类型 H ELISA, WB Rb Polyclonal Antibody 描述 产品目录编号 AB15510 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Neuroligin 2 Antibody 背景信息 Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. 产品信息 演示 Liquid in PBS with 0.1% BSA. 应用 应用 Anti-Neuroligin 2 Antibody is an antibody against Neuroligin 2 for use in WB, ELISA. 主要应用 - ELISA
- Western Blotting
应用说明 Western blot: 1-10 μg/mL using ECL.
Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 μg/mL
ELISA: 1:10,000-1:100,000 using 50-100 ng of control peptide/well.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide near the C-terminus of human Neuroligin 2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Neuroligin 2 (NLGN2). 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_020795.2
Entrez基因汇总 This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. 基因符号 - KIAA1366
- NLGN2
UniProt编号 - Q8NFZ4
UniProt汇总 FUNCTION: SwissProt: Q8NFZ4 # Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures.
SIZE: 835 amino acids; 90820 Da
SUBUNIT: Interacts with neurexin 1-beta, neurexin 2-beta and neurexin 3-beta. Interacts with INADL (By similarity). Probably interacts through its C-terminus with DLG4 third PDZ domain.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).
SIMILARITY: SwissProt: Q8NFZ4 ## Belongs to the type-B carboxylesterase/lipase family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µg
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下一件merck millipore产品：merck millipore,默克密理博,AB211-ML-KC,Goat Anti-Rabbit IgG Fc Gamma Fraction (100mL) KC
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