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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB15466 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Zic3 Antibody Alternate Names - Zinc finger protein Zic3
产品信息 格式 Affinity Purified 演示 Liquid in PBS with 0.1% sodium azide. 应用 应用 This Anti-Zic3 Antibody is validated for use in WB for the detection of Zic3. 主要应用 - Western Blotting
应用说明 Western blot: 1.0-5.0 μg/mL on human brain lysate.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide 宿主 Rabbit 特异性 Zic3 (Zinc finger protein). By Western blot the antibody recognizes a band at ~56 kDa in human brain lysate. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_003413.2
Entrez基因汇总 This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. 基因符号 - HTX
- ZIC3
- HTX1
- ZNF203
纯化方法 Immunoaffinity purified UniProt编号 - O60481
UniProt汇总 FUNCTION: SwissProt: O60481 # Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation.
SIZE: 467 amino acids; 50569 Da
SUBCELLULAR LOCATION: Nucleus.
DISEASE: SwissProt: O60481 # Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1) [MIM:306955]. HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs, including asplenia or polysplenia, symmetric liver, intestinal malrotation, and abnormal lung lobation.
SIMILARITY: SwissProt: O60481 ## Belongs to the GLI C2H2-type zinc-finger protein family. & Contains 4 C2H2-type zinc fingers.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. 包装信息 数量 100 µg
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