• merck millipore,默克密理博,14-924M,TYK2 Protein, active, 250 µg
  • merck millipore,默克密理博,14-924M,TYK2 Protein, active, 250 µg

    产品名称:TYK2 Protein, active, 250 µg
    产品型号:14-924M
    Active, TN-terminal 6His-tagged, recombinant, human TYK2, amino acids 875-end. For use in Kinase Assays.

    merck millipore,默克密理博,14-924M,TYK2 Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-924M,TYK2 Protein, active, 250 µg

    描述
    产品目录编号 14-924M
    商名
    • Upstate
    描述 TYK2 Protein, active, 250 µg
    概述 TYK2 is member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
    产品信息
    演示 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
    应用
    应用 Active, TN-terminal 6His-tagged, recombinant, human TYK2, amino acids 875-end. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 N-terminal 6His-tagged, recombinant, human TYK2 amino acids 875-end, expressed by baculovirus in Sf21 insect cells.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_003331
    基因符号
    • JTK1
    • TYK2
    蛋白靶 TYK2
    纯化方法 Purified using immobilized metal affinity chromatography followed by gel filtration.
    靶子系列 TK
    UniProt编号
    • P29597
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of peptide GGMEDIYFEFMGGKKK
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 250 µg
    包装 Also available in 10μg size as catalog # 14-924 and in bulk as catalog # 14-924-K.

    merck millipore,默克密理博,14-924M,TYK2 Protein, active, 250 µg

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