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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB15224 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-SV2A Antibody Alternate Names - Synaptic vesicle glycoprotein 2A
产品信息 格式 Serum 演示 Liquid 应用 应用 Anti-SV2A Antibody detects level of SV2A & has been published & validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Synthetic peptide from rat. 宿主 Rabbit 特异性 SV2A. By Western blot the antibody recognizes a band at ~100 kDa in rat brain extract. 品种反应性 Rat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_014849.2
基因符号 - KIAA0736
- SV2A
- SV2
纯化方法 Serum UniProt编号 - Q7L0J3
UniProt汇总 FUNCTION: SwissProt: Q7L0J3 # Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
SIZE: 742 amino acids; 82695 Da
SUBUNIT: Interacts with SYT1/synaptotagmin-1 in a calcium- dependent manner. Binds the adapter protein complex AP-2 (By similarity).
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein (By similarity). Note=Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas (By similarity).
PTM: Phosphorylation by CK1 of the N-terminal cytoplasmic domain regulates interaction with SYT1 (By similarity). & N-glycosylated (By similarity).
SIMILARITY: SwissProt: Q7L0J3 ## Belongs to the major facilitator superfamily.
MISCELLANEOUS: Identified as the brain binding-site for the antiepileptic drug levetiracetam/lev.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20degC in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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下一件merck millipore产品：merck millipore,默克密理博,MABF552,Anti-CD27 Antibody (human), APC-Cy7, clone O323
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