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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB15190 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Neurofascin 186 Antibody 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in PBS with 0.1% sodium azide. 应用 应用 This Anti-Neurofascin 186 Antibody is validated for use in WB for the detection of Neurofascin 186. 主要应用 - Western Blotting
应用说明 Western blot: 0.1-1.0 μg/mL on extracts from mouse brain lysate.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Neurofascin 186. By Western blot the antibody recognizes a band at ~186 kDa in mouse brain lysate. 品种反应性 Mouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_015090.2
Entrez基因汇总 Neurofascin is an L1 family immunoglobulin cell adhesion molecule (see L1CAM; MIM 308840) involved in axon subcellular targeting and synapse formation during neural development (Ango et al., 2004 [PubMed 15479642]).[supplied by OMIM] 基因符号 - OTTHUMP00000065313
- NFASC
- OTTHUMP00000065315
- DKFZp686P2250
- FLJ46866
- OTTHUMP00000065305
- OTTHUMP00000065322
- KIAA0756
- OTTHUMP00000065324
- OTTHUMP00000065306
- OTTHUMP00000065307
- OTTHUMP00000065321
- NF
- neurofascin
- NRCAML
- OTTHUMP00000065308
纯化方法 Immunoaffinity purified UniProt编号 - O94856
UniProt汇总 FUNCTION: SwissProt: O94856 # Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions (By similarity).
SIZE: 1347 amino acids; 150027 Da
SUBUNIT: Probable constituent of a neurofascin/NRCAM/ankyrin-G complex. Associates with the sodium channel beta-1 (SCN1B) and beta-3 (SCN3B) subunits. Interacts with GLDN/gliomedin (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: O94856 ## Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. & Contains 5 fibronectin type-III domains. & Contains 6 Ig-like C2-type (immunoglobulin-like) domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. 包装信息 数量 100 µg
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