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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB15067 描述 Anti-EMX1 Antibody Alternate Names - empty spiracles homolog 1 (Drosophila)
- Empty spiracles homolog 1
- Empty spiracles-like protein 1
- empty spiracles homeobox 1
背景信息 EMX1 and EMX2 are human homologs to the Drosophila developmental genes empty spiracles, and are specifically expressed in the developing telencephalic cortex. During the process of proliferation, migration, differentiation, and maturation, it has been reported that, while EMX2 is expressed in the dorsal telencephalon and small diencephalic regions, EMX1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon and remains localized in most cells of the cerebral cortex. Since EMX1 is expressed in both proliferating and differentiating neurons in the developing embryonic brain, it has also been shown to be a reliable marker of the embryonic pyramidal cell lineages. 产品信息 格式 Affinity Purified 控制 - Human fetal brain lysates.
演示 Purified rabbit polyclonal in buffer containing PBS with 0.09% sodium azide. 应用 应用 Anti-EMX1 Antibody detects level of EMX1 & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Western Blotting:
Recommended working dilutions are 1:250 – 1: 500.生物信息 免疫原品种 Synthetic human EMX1 peptide, a.a. 274-290 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptided selected from human EMX1. 品种反应性 Human Species Reactivity Note Reacts with human. Comparison of sequence homology suggests that this antibody may also react with mouse, rat, canine, bovine, and equine; however, reactivity with other species has not been tested. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_004097.2
基因符号 - EMX1
纯化方法 Peptide affinity purified UniProt编号 - Q04741
UniProt汇总 FUNCTION: Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
SUBCELLULAR LOCATION: Nucleus (Probable).
TISSUE SPECIFICITY: Cerebral cortex.
SIMILARITY: Belongs to the EMX homeobox family.
SIMILARITY: Contains 1 homeobox DNA-binding domain.
产品使用声明 质量保证 Routinely evaluated by Western blot on human fetal brain lysates. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles. 包装信息 数量 100 µg
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